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If you have any questions about BYSTOLIC, ask your doctor or pharmacist. Drugs that inhibit CYP2D6 can be expected to increase plasma levels of nebivolol. When BYSTOLIC is co-administered with an inhibitor or an inducer of this enzyme, monitor patients closely and adjust the nebivolol dose according to blood pressure response. In vitro studies nebivolol online buy have demonstrated that at therapeutically relevant concentrations, d-and l-nebivolol do not inhibit any cytochrome P450 pathways. Neonates of women with hypertension, who are treated with beta-blockers during the third trimester of pregnancy, may be at increased risk for hypotension, bradycardia, hypoglycemia, and respiratory depression.